Epidermal necrolysis refers to severe cutaneous reactions that cause extensive necrosis of tissue and detachment of the epidermis. It encompasses three conditions which are on a continuum of severity and how much of the body’s surface area is affected:

  • Stevens-Johnson syndrome (SJS): Less than 10% of BSA is detached
  • Toxic epidermal necrolysis (TEN) – More than 30% of BSA is detached
  • SJS/TEN overlap: Between 10 and 30% of BSA is detached

In this episode you’ll learn: 

  • Epidermal necrolysis pathophysiology and risk factors
  • High risk medications that can cause SJS/TEN
  • Complications of SJS/TEN
  • Signs and symptoms in the prodromal and acute phase
  • Important assessment for a patient with SJS/TEN
  • Key tests utilized to diagnose and evaluate a patient with epidermal necrolysis
  • Treatments for SJS/TEN, including medications
  • Vital education components for patients and families


Full Transcript – Read the article and view references

FREE CLASS – If all you’ve heard are nursing school horror stories, then you need this class! Join me in this on-demand session where I dispel all those nursing school myths and show you that YES…you can thrive in nursing school without it taking over your life!

DICLearn more about disseminated intravascular coagulation in this episode!

Nursing School with a Chronic IllnessHear more from Christina Brown, RN and how she managed nursing school with a chronic illness.

Study Sesh – Change the way you study with this private podcast that includes dynamic audio formats that help you review and test your recall of important nursing concepts on-the-go. Free yourself from your desk with Study Sesh! 

Med Surg Solution – Are you looking for a more effective way to learn Med Surg? Enroll in Med Surg Solution and get lessons on 57 key topics and out-of-this-world study guides.

LATTE Method TemplateDownload the free LATTE Method Template so you can streamline how you study and focus on what a nurse needs to know.

💕Did you love this episode? Please take a moment to follow or subscribe to the show so you never miss an episode!


The information, including but not limited to, audio, video, text, and graphics contained on this website are for educational purposes only. No content on this website is intended to guide nursing practice and does not supersede any individual healthcare provider’s scope of practice or any nursing school curriculum. Additionally, no content on this website is intended to be a substitute for professional medical advice, diagnosis or treatment.